Research projects

AMICO

Aerobic or Muscle mass training to Improve Colorectal cancer Outcome

This three-arm Bayesian adoptive trial evaluates the effect of aerobic interval training vs. resistance exercise vs. usual care on chemotherapy treatment modification in patients with metastatic colorectal cancer.

EXENTRO

EXErcise during Neoadjuvant chemoradiation Treatment to improve Rectal and esophageal cancer Outcome

This pilot trial evaluates the feasibility of a three-arm RCT comparing twice weekly supervised aerobic and resistance exercise vs. 5-day weekly in hospital aerobic exercise vs. usual care during neoadjuvant chemoradiation treatment.

EXTRA

EXercise Tailored to patients with RAre cancer

This study evaluates the feasibility of a personalized physical therapist-guided exercise program in patients with rare cancer.

KINETICS

walKINg Exercise Training to reduce fatigue In Cancer Survivors

This quasi-experimental interrupted time-series design explores which physiological, psychological and biological factors mediate the walking exercise-induced changes in cancer-related fatigue.

PADOVA

Physical Activity and Dietary intervention in patients with OVArian cancer receiving chemotherapy

This RCT evaluates the effects of a combined exercise and dietary intervention vs. usual care in patients with ovarian cancer receiving (neo)adjuvant chemotherapy treatment on physical function and fatigue as primary outcomes, and quality of life and chemotherapy treatment modification as secondary outcomes.

Polaris

Predicting OptimaL cAncer Rehabilitation and Supportive care

This study includes an internationally shared and continuously growing database of individual patient data from RCTs that evaluated the effects of exercise and psychosocial interventions.
Currently dietary interventions are also included. This database is used for individual patient data meta-analyses to examine differences in intervention effects between patient subgroups.

STAPPS

Systemic Treatment-related toxicity identified with a smartphone APPlication measuring Step count

This observational study aims to study whether the level of physical activity measured with a smartphone is associated with clinically relevant adverse events in patients with advanced cancer receiving palliative systemic treatment.

SPRINT

Supervised exercise to Promote Infiltration of NK-cells into the Tumor

The objective of this pilot RCT is to study the feasibility in terms of patient enrolment and the percentage of tumor biopsies that can be examined successfully, and 2) generate preliminary data on the potential effects of exercise on immune function assessed in the tumor and in blood.

PLAYA

Personalized Lifestyle support for Adolescents and Young Adults with cancer

This project aims to advance personalized, lifestyle-based cancer care for adolescent and young adults (AYA) with cancer by mapping exercise and dietary behavior over time, evaluating the impact of targeted interventions on fatigue and quality of life, and uncovering individual needs in AYAs with cancer.

PRIME-R

Promoting Response to IMmunotherapy by Exercise in patients with advanced Renal cell Carcinoma

This pilot RCT aims to study the feasibility, safety, and immunological effects of supervised exercise vs usual care during treatment with immune checkpoint inhibitor therapy in patients with advanced renal cell carcinoma.

Exercise Oncology Research Group